Jakarta, goldensamoyed Indonesia
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Technology
genomics
(genomics) is now a breakthrough in the world of modern health.By studying a person’s entire gene sequence, genomics provides a deep understanding of how diseases arise, develop, and how best to treat them.
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National Human Genome Research Institute
, each person has genetic variations that make the body’s response to drugs, diseases, or lifestyle different from each other.This is the basis of personalized medicine, or personalized treatment.
In simple terms, genomics looks at the human body through its ‘biological imprint’.Genomics has changed the way doctors assess a person’s health risks.Instead of waiting for symptoms to appear, this technology allows early detection at the DNA level.
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By knowing small changes in genes, doctors can predict a person’s tendency to experience certain diseases.Starting from heart disease, diabetes, to cancer.
Disease prediction from DNA
One application of genomics that is starting to be widely researched is the polygenic risk score, a method for calculating how big a person’s risk of developing common diseases.This score is derived from thousands to millions of small gene variations that each contribute little by little to risk.
People with a high risk score can immediately take preventive measures, for example improving their diet, increasing physical activity, or undergoing routine examinations earlier.If implemented widely, this approach has the potential to save many lives.
Genomics also paves the way for gene therapy, a treatment method that directly repairs disease-causing DNA mutations.
One of gene therapy’s greatest successes has been in sickle cell disease, an inherited blood disease that causes red blood cells to change shape and restrict blood flow.By repairing the damaged gene, patients can experience remarkable improvements, some even being declared cured.
The same technology is now being developed for various other genetic diseases, such as cystic fibrosis and Duchenne muscular dystrophy.This provides hope for a group of diseases that were previously difficult to treat.
This rapid development certainly comes with challenges.Issues regarding data privacy, the ethics of gene manipulation, and equality of access are still being discussed.The reason is that genomics concerns the most personal information, namely a person’s DNA, research and application must of course be carried out carefully and responsibly.
Even so, the Director of Sales and Marketing at Bethsaida Healthcare, Iwan A. Setiawan, said that genomic research and gene-based treatment is not impossible to implement in Indonesia.This is because increasingly inclusive methods and increasingly affordable technology make experts optimistic that the benefits will be felt more widely in the future.
According to him, the development of genomics-based services requires a strong and accurate medical data foundation.However, the benefits will be enormous, especially for patients with chronic diseases.
“Patients who appear to have the same disease may need different treatment. Therefore, doctors need a correct diagnosis based on evidence and electronic data,” he said in a statement at the Paramount Enterprise Anniversary Media Gathering, Thursday (13/11).
He added that data integration, from laboratories, drugs, to digital medical records will support the delivery of DNA and genomic-based therapies with more precision.
“With increasing research and clinical applications, genomics is no longer just a technology of the future. It is here and changing the way we understand health, providing opportunities to prevent disease earlier, choose the most suitable therapy, and even repair the DNA that causes disease,” he said.
(tis/tis)
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